Last Date: 28 May 2023.
We are looking for a highly motivated and dynamic researcher who has a strong profile within molecular pharmacology of G protein-coupled receptors (GPCRs) for a 13 months position commencing 1 September 2023 or as soon as possible thereafter.
The Postdoc will work in the Molecular Pharmacology group led by Associate Professor Alexander Hauser (https://drug.ku.dk/disciplines/molecular-and-cellular-pharmacology/molecular_pharmacology/) on an ambitious project funded by the Lundbeck Foundation entitled “Advancing personalised medicine for psychiatric diseases through integrative GPCR pharmacogenomics”. The overall objective of the project is to provide a basis for genetics-based personalised drug prescriptions for some of the most commonly used CNS drugs acting on GPCRs, and to create a public research platform to characterise GPCR genetic variants.
Information on the department can be found at: https://drug.ku.dk.
Our research
The Hauser group focuses on both computational and experimental approaches to genetics, genomics, structural biology, pharmacology, and drug development. Integrated into this research environment, the group uses state-of-the-art approaches to the molecular pharmacology of G protein-coupled receptors. A major focus is integrated pharmacogenomics, in which experimental in vitro data from our laboratories is cross-linked with biobank data. The group currently consists of 10-15 members, and co-affiliated researchers from groups within the Faculty of Health & Medical Sciences.
Your job
The Postdoc will play an important role in determining how psychiatric drug responses are affected by genetic variations by molecular pharmacological characterization of GPCR genetic variants in recombinant cell lines using a range of state-of-the-art assays. Part of the work will be to apply a developed and efficient assay pipeline to efficiently characterize multiple psychiatric drugs on multiple GPCR genetic variants.
Profile
We are looking for a highly motivated and enthusiastic scientist with the following competencies and experience:
Essential experience and skills:
- You have a PhD in pharmacology, pharmaceutical sciences or related science
- You are highly experienced in molecular pharmacological characterization of G protein-coupled receptors
- Mammalian cell culture
- Demonstrated ability to independently learn new concepts and solve biological problems
- Proficient communication skills and ability to work in interdisciplinary teams
- Excellent English skills written and spoken
Desirable experience and skills:
- G protein-coupled receptor pharmacological assay development/optimization
- screening of ligand and/or mutant libraries
- You have an active interest in pharmacological profiling of drugs and mutants in the context of personalized medicine
- analyses of pharmacological data using the GraphPad Prism software package
- publication in leading journals related to the research project
- Experience in the application of FRET- and BRET-based approaches to GPCR pharmacology
Place of employment
The place of employment is at Department of Drug Design and Pharmacology, University of Copenhagen. We offer creative and stimulating working conditions in dynamic and international research environment. Our research facilities include modern laboratories and and state-of-the-art equipment.
Terms of employment
The employment as postdoc is a full time and fixed-term position for 13 months. Starting date is 1 September 2023 or as soon as possible thereafter.
Salary, pension and terms of employment will be in accordance with the agreement between the Danish Ministry of Finance and AC (Danish Confederation of Professional Associations). Currently, the monthly salary starts at 36,200 DKK/ approx. 4,800 Euro (April 2023-level). Depending on qualifications, a supplement may be negotiated. The employer will pay an additional 17.1 % to your pension fund.
Non-Danish and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark the last 10 years.
The position is covered by the Job Structure for Academic Staff at Universities 2020.
Questions
For further information please contact Associate Professor Alexander Hauser; e-mail [email protected]; www.sund.ku.dk
Foreign applicants may find this link useful: www.ism.ku.dk (International Staff Mobility).
Application procedure
Your online application must be submitted in English by clicking ‘Apply now’ below. Furthermore your application must include the following documents/attachments – all in PDF format:
- Motivated letter of application (max. one page).
- CV incl. education, work/research experience, language skills and other skills relevant for the position.
- A certified/signed copy of a) PhD certificate and b) Master of Science certificate. If the PhD is not completed, a written statement from the supervisor will do.
- List of publications.
Application deadline: 28 May 2023, 23.59pm CET
We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.
The further process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.
You can read about the recruitment process at https://employment.ku.dk/faculty/recruitment-process/
The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.
Interviews are expected to be held mid-June 2023.
University of Copenhagen wish to reflect the diversity of society and welcome applications from all qualified candidates regardless of age, disability, gender, nationality, race, religion or sexual orientation. Appointment will be based on merit alone.
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