Clinical Research Fellow, Implanted Cardiac Devices and Physiological Pacing Research, Imperial College London, London, UK

Last Date: 15 September 2023

Job description

Job summary

This role is for a Fellowship (Clinical Research Fellow in Implanted Cardiac Devices and Physiological Pacing Research) to undertake research in the field of Pacing Induced Cardiomyopathy. The successful candidate could come from a medical or allied medical background e.g. cardiac physiologist.

The aims of this research program are through collaboration with clinical teams across the country to:

-Improve the assessment and diagnosis of Pacing Induced Cardiomyopathy.

-Further our understanding of the mechanisms of Pacing Induced Cardiomyopathy and if these mechanisms can be reversed and by what means.  

-Gain mechanistic insights on the contribution of both change in cardiac activation pattern and reverse remodelling to the development of Pacing Induced Cardiomyopathy.

The appointed Fellow, funded by Abbott Laboratories Ltd, will take a leading role in Clinical Research Trials funded by the British Heart Foundation and Heart Research UK run by our research team at the National Heart and Lung Institute.

These trials focus on determining the optimal pacing approach for patients with bradycardia pacing indications, understanding the mechanisms leading to a decline in cardiac function and patient quality of life. Determining the best approach to track change in clinical status of pacemaker recipients. Potentially exploring the role of genetics and novel biomarkers in predicting the development of cardiomyopathy in individuals. Exploring the symptomatic benefit of upgrading patients with chronic RV pacing and mild-moderate LV impairment, the feasibility of upgrading such patients and the safety of such upgrade procedures.

The post will offer excellent advanced research training and would attract a high-calibre individual who would become a major asset to this scientific and clinical field. Through research activity and experiential learning the Fellowship will advance the field of cardiac devices with linked improvements in health outcomes and care for patients.

Duties and responsibilities

You will gain advanced skills and understanding of CIED implant indications, novel pacing approaches, device programming and device optimisation approaches. Interested candidates will also gain experience in implant techniques.

You will undertake research in the field of Pacing Induced Cardiomyopathy. The aims of this research program are to collaborate with clinicians across the country to improve the assessment and diagnosis of Pacing Induced Cardiomyopathy. To further our understanding of the mechanisms of Pacing Induced Cardiomyopathy and in whom these mechanisms can be reversed and by what means. 

You will support the running of the PROTECT-UP trial, which will include providing clinical supervision of investigations and collection of clinical data

Essential requirements

You should have a Bachelor’s degree or equivalent in biomedical / scientific field or medical field, and clinical experience with implantable cardiac devices including device programming, and follow-up

Ideally, you will have experience in the cardiac catheter laboratory, knowledge of pacemaker programming, general laboratory practice, technique and instrumentation.

Further information

This position is full-time, fixed-term, available for 3 years. 

All candidates need to complete an online application.

 Should you require any further details on the role please contact Dr Daniel Keene,  [email protected]

 As this post is exempt from the Rehabilitation of Offenders Act 1974, a satisfactory Disclosure and Barring Service (DBS) check, at the appropriate level, will be required for the successful candidate.

 The College is a proud signatory to the San-Francisco Declaration on Research Assessment (DORA), which means that in hiring and promotion decisions, we evaluate applicants on the quality of their work, not the journal impact factor where it is published. For more information, see https://www.imperial.ac.uk/research-and-innovation/about-imperial-research/research-evaluation/

 The College believes that the use of animals in research is vital to improve human and animal health and welfare. Animals may only be used in research programmes where their use is shown to be necessary for developing new treatments and making medical advances. Imperial is committed to ensuring that, in cases where this research is deemed essential, all animals in the College’s care are treated with full respect, and that all staff involved with this work show due consideration at every level.

http://www.imperial.ac.uk/research-and-innovation/about-imperial-research/research-integrity/animal-research

 Imperial College is committed to equality of opportunity, to eliminating discrimination and to creating an inclusive working environment. We are an Athena SWAN Silver award winner, a Stonewall Diversity Champion, a Disability Confident Employer and work in partnership with GIRES to promote respect for trans people.

About Imperial College London

Imperial College London is the UK’s only university focussed entirely on science, engineering, medicine and business and we are consistently rated in the top 10 universities in the world.

You will find our main London campus in South Kensington, with our hospital campuses located nearby in West and North London. We also have Silwood Park in Berkshire and state-of-the-art facilities in development at our major new campus in White City.

We work in a multidisciplinary and diverse community for education, research, translation and commercialisation, harnessing science and innovation to tackle the big global challenges our complex world faces.

It’s our mission to achieve enduring excellence in all that we do for the benefit of society – and we are looking for the most talented people to help us get there.

Additional information

Please note that job descriptions cannot be exhaustive, and the post-holder may be required to undertake other duties, which are broadly in line with the above key responsibilities.

Imperial College is committed to equality of opportunity and to eliminating discrimination. All employees are expected to follow the Imperial Values & Behaviours framework. Our values are: 

  • Respect              
  • Collaboration
  • Excellence          
  • Integrity
  • Innovation

In addition to the above, employees are required to observe and comply with all College policies and regulations.

We are committed to equality of opportunity, to eliminating discrimination and to creating an inclusive working environment for all. We therefore encourage candidates to apply irrespective of age, disability, marriage or civil partnership status, pregnancy or maternity, race, religion and belief, gender reassignment, sex, or sexual orientation. We are an Athena SWAN Silver Award winner, a Disability Confident Leader and a Stonewall Diversity Champion.

For technical issues when applying online please email [email protected].

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