Last Date: 17 September 2023.
Applications are invited for a Research Associate to work in the group of Prof Maria Grazia Spillantini, on a project testing the efficacy of a new compound to reduce alpha-synuclein aggregation and its effects, in a mouse model of Parkinson’s disease”.
Funding is available for 18 months. The appointee will work on a Parkinson’s UK Drug Accelerator award which cover a collaboration between the Spillantini’s lab and Professor Arianna Bellucci at the University of Brescia, Italy.
The postdoctor will work in the group of Maria Grazia Spillantini using transgenic mice to determine the ability of the drug to reduce alpha-synuclein aggregation and prevent development of dopaminergic dysfunction.
Experience on Parkinson’s disease mouse models, dopaminergic system, drug pharmacology, mouse behavioural studies as well as immunohistochemistry is required. We welcome candidates from all backgrounds and value a supportive environment.
Duties and responsibilities
- Drug administration and evaluation of its effect using immunohistochemical, biochemican and behavioural experiments. The essential requirements for this post are as follows:
- Hold a PhD
- Strong interest in the project
- Strong track record of high-quality independent research, commensurate with career stage
Experience in:
- Alpha-synuclein and its synaptic pathology is required.
Experience and knowledge in one or more of the following topics is desirable:
- Parkinson’s disease mouse models,
- Immunohistochemistry
- Stereology
- Behavioural tests
The position is full time and fixed term for 18 months. The applicant will be based at the Clifford Allbutt Building in the Department of Clinical Neurosciences at the University of Cambridge and travel to the University of Brescia will be occasionally required.
The post is available from 1st December 2023.
For questions relating to the post, please contact Prof Maria Grazia Spillantini at [email protected]
Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment and a security check.
Click the ‘Apply’ button below to register an account with our recruitment system (if you have not already) and apply online.
Applicants must have (or be close to obtaining) a PhD.
Appointment at Research Associate level is dependent on having a PhD. Those who have submitted but not yet received their PhD will initially be appointed as a Research Assistant (Grade 5, Point 38 £31,411) moving to Research Associate (Grade 7) upon confirmation of your PhD award.
Please ensure that you upload a covering letter and CV in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.
Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.
Please quote reference ZE38323 on your application and in any correspondence about this vacancy.
The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.
The University has a responsibility to ensure that all employees are eligible to live and work in the UK.
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