Last Date: January 15th 2024.
Human Technopole (HT) is an interdisciplinary life science research institute, created and supported by the Italian Government, with the aim of developing innovative strategies to improve human health. HT is composed of five Centers: Neurogenomics, Computational Biology, Structural Biology, Genomics, and Health Data Science. The Centers work together to enable interdisciplinary research and to create an open, collaborative environment that will help promote life science research both nationally and internationally.
About the lab:
The thyroid gland is a natural bioreactor where rare iodine from the diet is accumulated and used to synthesise thyroid hormones, essential iodinated molecules for the metabolism and development in all vertebrates. In humans, thyroid dysfunction severely impacts cardiovascular homeostasis, metabolism, brain development and function, with increasing incidence Worldwide. Currently, our understanding of molecular events behind thyroid hormone synthesis is far from complete and consequently of major thyroid diseases. The lab mission is to pioneer and set up robust biochemical, cellular and structural biology (cryo-EM) workflows to reveal thyroid molecular mechanisms in detail and across scales and time (from atoms to organoids). This project was recently awarded an ERC starting grant “THYROMOL” https://erc.europa.eu/news/erc-starting-grants-2021-project-highlights.
More details on the group are found here: https://humantechnopole.it/en/research-groups/coscia-group/
See previous work on the research topics of this call:
Key tasks and responsibilities:
- To carry out the scientific project prioritising tasks and respecting deadlines, by reporting to the group leader
- To positively interact and collaborate with the research group members
- To foster development of new ideas on the projects, generating new tools and protocols to be also shared within the team
- Digital lab book recording and sample tracking (for example cloning database)
- Writing scientific publications and regular reports
- Providing scientific support and guidance to (junior) lab members.
Job requirements
Essential requirements:
- Fluency in English
- Proficiency in mammalian cell culture
- Proficiency in cellular light imaging
- Experience in protein biochemistry and molecular biology
Preferential requirements:
- Experience in the study of protein complexes in mammalian cells (Proximity ligation, pull down assays and related techniques)
- Experience in live imaging
- Protein purification and in vitro activity assays
Application Instructions
To apply, please send the following:
- a CV.
- a motivation letter in English relating your track record to the specifics of the call.
- names and contacts of 2 referees.
Why Human Technopole:
HT seeks scientific excellence, we recruit the best scientific talents through international, open calls.
Our working environment is international, friendly and inclusive. Our scientists work together across disciplines on research topics of biomedical relevance, leveraging synergies between their diverse skillsets and methodological approaches.
We believe that highly diverse teams yield the best and most innovative results.
We engage in outward-facing scientific activities aimed at benefiting the national and international research community. Training is also at the heart of our activity, with initiatives and opportunities for our staff, including scientific courses, conferences and workshops.
Main benefits
- Welfare plans.
- Canteen service.
- Work-life balance provisions.
- Italian language training for foreigners.
- Parental leave up to 1 year and other support for new parents.
- Counseling.
- Flexible working hours.
- Remote working policy.
- Support for relocation.
- Researchers coming to Italy for the first time, or returning after residing abroad, benefit from very attractive income tax benefits.
Special consideration will be given to candidates who are part of the protected categories list, according to L. 68/99.
Number of positions offered: 1
Contract offered: CCNL Chimico Farmaceutico, Fixed-term 4 years – employee level.
The position is based in Milan.
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